이진 교수
학력
1986한양대학교 의과대학 졸업 1990한양대학교 일반대학원 의학 석사 1996한양대학교 일반대학원 의학(내과학전공) 박사 |
경력
한양대학교병원 내과 전공의 및 전문의 수료 소화기내과 분과 / 소화기내시경 전문의 2000 ~ 2001미국 워싱턴주립대학 소화기내과 연수 한림대학교한강성심병원 내과 / 소화기내과 과장 및 기획실장 역임 한림대학교동탄성심병원 내과 과장 및 진료부원장 역임 한림대학교동탄성심병원 소화기센터장 한림대학교 의과대학 내과학교실 주임교수 |
학회활동
대한소화기내시경학회 편집이사 및 편집장 대한소화기내시경학회 경인지회 부회장 대한소화기학회 부회장 대한췌장담도학회 정보전산이사 대한췌장담도학회 감사 ~ 2022대한췌장담도학회 이사장 대한내과학회 / 대한소화기학회 / 대한소화기내시경학회 / 대한췌장담도학회 평의원 대한내과학회, 대한소화기학회, 대한소화기내시경학회, 대한췌장담도학회, 대한간학회 평생(정)회원 |
수상이력
성심학술상 대한소화기학회 SK연구상 |
논문/저서
|
국내학회지 발표논문 1. 이진ㆍ고동희. 췌장염에 있어서 유전적 특징: 한국과 다른 나라의 차이점이 있는가? 대한췌담도학회지 2014;19(1);13-17 2. 고동희, 김종혁, 이진, 최호순. 급성 췌장염 진료 권고안: 급성 췌장염의 진단. 대한췌담도학회지 2013;18(2);4-13 3. Choi MH, Lee KH, Ryu JH, Han SY, Byun HW, Koh DH, Jang HJ, Eun CS, Kae SH, Lee J. The Usefulness of Double Balloon Enteroscopy for Diagnosis and Treatment of Small Bowel Diseases. Intest Res. 2008 Jun;6(1):31-36. 4. Jang HJ, Park CH, Han SY, Byun HW, Choi MH, Kae SH, Lee J. Comparison of Double Balloon Enteroscopy and Capsule Endoscopy for Patients with Suspected Small Bowel Diseases. Korean J Gastrointest Endosc. 2007 Dec;35(6):379-384. 5. Jang HJ, Choi MH, Kim YS, Seo YA, Baik KH, Baik IH, Eun CS, Kim JB, Kae SH, Kim DJ, Lee MS, Kim HY, Lee J. Effectiveness of Triple Therapy and Quadruple Therapy for Helicobacter pylori Eradication. Korean J Gastroenterol. 2005 Nov;46(5):368-372. 6. Kim GS, Jang HJ, Eun CS, Kae SH, Park WJ, Chun W, Kim JH, Lee J. The Clinical Features of Upper Gastrointestinal Bleeding after Acute Burn Injury. Korean J Gastrointest Endosc. 2005 Aug;31(2):77-83. 7. Jang HJ, Kim JH, Hong SJ, Kae SH, Lee J, Lee MS, Kim WJ, Kim DJ, Kim HY, Park CK, Yoo JY. Does the Eradication for Helicobacter pylori Deteriorate Reflux Esophagitis?. Korean J Gastroenterol. 2002 Feb;39(2):88-92. 8. Jang HJ, Kim JH, Hong SJ, Kang SS, Kae SH, Lee J, Joo SA. Relationship between the Telomerase Activation and Helicobacter pylori Infection in Benign and Precancerous Lesion of the Stomach. Korean J Gastroenterol. 2001 Jul;38(1):15-22. 9. Dong SH, Lee J, Koh DH, Choi MH, Jang HJ, Kae SH. Pravastatin activates PPARalpha/PPARgamma expression in the liver and gallbladder epithelium of hamsters. Hepatobiliary Pancreat Dis Int. 2011 Apr;10(2):185-90. 10. Lee J, Hong EM, Koh DH, Choi MH, Jang HJ, Kae SH, Choi HS. HMG-CoA reductase inhibitors (statins) activate expression of PPARalpha/PPARgamma and ABCA1 in cultured gallbladder epithelial cells. Dig Dis Sci. 2010 Feb;55(2):292-9. Epub 2009 Feb 19. 11. Lee J, Hong EM, Byun HW, Choi MH, Jang HJ, Eun CS, Kae SH, Choi HS. The effect of PPARalpha and PPARgamma ligands on inflammation and ABCA1 expression in cultured gallbladder epithelial cells. Dig Dis Sci. 2008 Jun;53(6):1707-15. 12. Jang HJ, Kim JH, Song HH, Woo KH, Kim M, Kae SH, Lee J, Cho JW, Kang JH, Lee SI, Gong SJ, Lee JA, Zang DY. Clinical outcomes of patients with liver cirrhosis who underwent curative surgery for gastric cancer: a retrospective multi-center study. Dig Dis Sci. 2008 Feb;53(2):399-404. Epub 2007 Jun 28. 13. Jang HJ, Kim GS, Eun CS, Kae SH, Jang WY, Lee J. Development of primary biliary cirrhosis in a patient with Crohn's disease: a case report and review of the literature. Dig Dis Sci. 2005 Dec;50(12):2335-7. 14. Lee SJ, Park JY, Kwon SA, Koh DH, Choi MH, Jang HJ, Kae SH, Lee J. A case of pneumatosis cystoids intestinalis with polymyositis. Korean J Gastroenterol. 2011 Apr;57(4):249-52. 15. Park JY, Lee J, Lee SJ, Kwon SA, Koh DH, Choi MH, Jang HJ, Kae SH. Spontaneous Biloma Caused by Pancreatic Cancer and Treated by Endoscopic Biliary Stenting. Korean J Gastrointest Endosc. 2011 Mar;42(3):190-194. 16. Lee SH, Koh DH, Park SW, Kim JY, Kim YW, Jang HJ, Kae SH, Lee J. A Case of Hemosuccus Pancreaticus Mistaken for Hemobilia. Korean J Gastrointest Endosc. 2009 Dec;39(6):389-392. 17. Lim YJ, Lee J, Yang JH, Koh DH, Choi MH, Jang HJ, Jang WY, Kae SH. A Case of a Cavernous Hemangioma in the Distal Jejunum Detected by Double-Balloon Enteroscopy in a Patient with Small Bowel Obstruction. Korean J Gastrointest Endosc. 2008 Oct;37(4):284-287. 18. Choi MH, Lee KH, Ryu JH, Han SY, Byun HW, Koh DH, Jang HJ, Eun CS, Kae SH, Lee J. The Usefulness of Double Balloon Enteroscopy for Diagnosis and Treatment of Small Bowel Diseases. Intest Res. 2008 Jun;6(1):31-36. 19. Byun HW, Lee J, Lim YJ, So CS, Han SY, Choi MH, Jang HJ, Kae SH. A Case of Brunner's Gland Hyperplasia of the Duodenal Second Portion with Annular Stricture Causing an Induced Obstruction. Korean J Gastrointest Endosc. 2008 Jan;36(1):27-30. 20. Jang HJ, Park CH, Han SY, Byun HW, Choi MH, Kae SH, Lee J. Comparison of Double Balloon Enteroscopy and Capsule Endoscopy for Patients with Suspected Small Bowel Diseases. Korean J Gastrointest Endosc. 2007 Dec;35(6):379-384. 21. Choi MH, Choi CY, Byun HW, Jang HJ, Eun CS, Jang WY, Lee JJ, Kae SH, Lee J. A Case of Gastrointestinal Stromal Tumor of the Proximal Jejunum Diagnosed by Double Balloon Enteroscopy. Korean J Gastrointest Endosc. 2006 Sep;33(3):163-167. 22. Choi MH, Ko YS, Kim MJ, Park SH, Chae YJ, Jang HJ, Eun CS, Kae SH, Lee J. A Case of Dieulafoy's Lesion in the Jejunum Treated by Double Balloon Enteroscopy. Korean J Gastrointest Endosc. 2006 Jun;32(6):392-396. 23. Choi CY, Chae YJ, Kim JY, Shin HW, Choi MH, Jang HJ, Eun CS, Kae SH, Lee J. A Case of Synchronous Triple Primary Cancer of Gastric Adenocarcinoma, Carcinoid Tumor of the Ampulla of Vater and Renal Cell Carcinoma. Korean J Gastrointest Endosc. 2006 Feb;32(2):136-140. 24. Chae YJ, Choi CY, Kim JY, Shin HW, Kim YS, Choi MH, Jang HJ, Eun CS, Kae SH, Lee J. Caroli's Disease Combined with Colon Cancer and Polycystic Kidney Disease. Korean J Gastrointest Endosc. 2006 Jan;32(1):71-74. 25. Jang HJ, Choi MH, Kim YS, Seo YA, Baik KH, Baik IH, Eun CS, Kim JB, Kae SH, Kim DJ, Lee MS, Kim HY, Lee J. Effectiveness of Triple Therapy and Quadruple Therapy for Helicobacter pylori Eradication. Korean J Gastroenterol. 2005 Nov;46(5):368-372. 26. Kim GS, Jang HJ, Eun CS, Kae SH, Park WJ, Chun W, Kim JH, Lee J. The Clinical Features of Upper Gastrointestinal Bleeding after Acute Burn Injury. Korean J Gastrointest Endosc. 2005 Aug;31(2):77-83. 27. Jang HJ, Byun HW, Choi MH, Kim GS, Eun CS, Kae SH, Lee J. A Case of Proximal Jejunal Diverticular Bleeding Diagnosed by Double Balloon Enteroscopy and Treated by Colonoscopic Hemoclipping. Korean J Gastrointest Endosc. 2005 May;30(5):273-276. 28. Suh YA, Jang HJ, Eun CS, Jang WY, Lee JJ, Kae SH, Lee J. A Case of a Submucosal Tumor in the Ascending Colon Probably Caused by Anisakis. Korean J Gastrointest Endosc. 2004 Apr;28(4):202-207. 29. Choi MH, Ryu JH, Suh YA, Jang HJ, Eun CS, Kae SH, Lee J. A Case of Retroperitoneal Paraganglioma Accompanying Bile Duct Dilatation. Korean J Gastrointest Endosc. 2003 Dec;27(6):558-562. 30. Ryu JH, Choi MH, Kim GS, Choi CS, Suh YA, Jang HJ, Eun CS, Kae SH, Lee J. A Case of Granular Cell Tumor of the Ascending Colon. Korean J Gastrointest Endosc. 2003 Jun;26(6):439-442. 31. Jang HJ, Kim JH, Hong SJ, Kae SH, Chae SW, Sohn JH, Lee J. A Case of Idiopathic Adulthood Ductopenia. Korean J Gastroenterol. 2002 Mar;39(3):233-237. 32. Jang HJ, Kim JH, Hong SJ, Kae SH, Lee J, Lee MS, Kim WJ, Kim DJ, Kim HY, Park CK, Yoo JY. Does the Eradication for Helicobacter pylori Deteriorate Reflux Esophagitis?. Korean J Gastroenterol. 2002 Feb;39(2):88-92. 33. Jang HJ, Kim JH, Hong SJ, Kang SS, Kae SH, Lee J, Joo SA. Relationship between the Telomerase Activation and Helicobacter pylori Infection in Benign and Precancerous Lesion of the Stomach. Korean J Gastroenterol. 2001 Jul;38(1):15-22. 34. Kim CU, Cho JW, Song JY, Jin DK, Hong SJ, Kae SH, Lee J, Joo SA. A Case of Ascites by Pseudomembranous Colitis, Initially Diagnosed Malignant Asites. Korean J Gastrointest Endosc. 2001 Apr;22(4):225-228. 국제학회지 발표논문 1. J Lee, EM Hong, JH Kim, JH Kim, JH Jung, Ursodeoxycholic acid shows antineoplastic effects in bile duct cancer cells via apoptosis induction; p53 activation; and EGFR-ERK, COX-2, and PI3K-AKT pathway inhibition. Mol Biol Rep 2021;48(9):6231-6240. 2. Effect of Nonsteroidal Anti-inflammatory Agents on Small Intestinal Injuries as Evaluated by Capsule Endoscopy. Lee SP, Lee J, Kae SH, Jang HJ, Jung ES.Dig Dis Sci. 2021;66(8):2724-2731 3. Jung J.H./Park S.W./Hyun B./Lee J./Koh D.H./Chung D. Identification of risk factors for obstructive cholecystitis following placement of biliary stent in unresectable malignant biliary obstruction: a 5-year retrospective analysis in single center. Surg Endosc. 2021;35(6):2679-2689 4. ES Jung, HJ Jang, EM Hong, HL Lim, SP Lee, SH Kae, J Lee, The Protective Effect of 5-Aminosalicylic Acid against Non-Steroidal Anti-Inflammatory Drug-Induced Injury through Free Radical Scavenging in Small Intestinal Epithelial Med. Lith. 2020;56(10):pp.515 5. JH Jung, BM Hyun, J Lee, DH Koh, JH Kim, SW Park, Neurologic Safety of Etomidate-Based Sedation during Upper Endoscopy in Patients with Liver Cirrhosis Compared with Propofol: A Double-Blind, Randomized Controlled Trial. J. Clin. Med. Vol. 9(8) pp.2424, 2020 6. HS Kim, JH Kim, HJ Jang, J Lee, The addition of metformin to systemic anticancer therapy in advanced or metastatic cancers: a meta-analysis of randomized controlled trials. Int. J. Med. Sci. Vol. 17(16) pp.2551~2560, 2020 7. JH Jung, SW Park, BM Hyun, J Lee, DH Koh, DC Chung, Identification of risk factors for obstructive cholecystitis following placement of biliary stent in unresectable malignant biliary obstruction: a 5-year retrospective analysis in single center. Surg. Endosc. Vol. 35(6) pp.2679~2689, 2020 8.SP Lee, J Lee, SH Kae, HJ Jang, DH Koh, JH Jung, SJ Byeon, The role of linked color imaging in endoscopic diagnosis of Helicobacter pylori associated gastritis. Scand. J. Gastroenterol. Vol. 55(9) pp.1114~1120, 2020 9. Lee J, Hong EM, Kim JH, Jung JH, Park SW, Koh DH, Choi MH, Jang H1, Kae SH. Metformin Induces Apoptosis and Inhibits Proliferation through the AMP-Activated Protein Kinase and Insulin-like Growth Factor 1 Receptor Pathways in the Bile Duct Cancer Cells. J Cancer. 2019 Apr 5;10(7):1734-1744 10. Jang HJ, Kim HS, Kim JH, Lee J. The Effect of Statin Added to Systemic Anticancer Therapy: A Meta-Analysis of Randomized, Controlled Trials. J Clin Med. 2018 7(10):325. 11. Park CH, Park SW, Hyun B, Lee J, Kae, SH, Jang, HJ, Koh DH, Choi MH. Efficacy and safety of etomidate-based sedation compared with propofol-based sedation during ERCP in low-risk patients: a double-blind, randomized, noninferiority trial. Gastrointest Endosc. 2018 Jan;87(1):174-184 12. Kim JH, Kim BJ, Jang HJ, Lee J. Molecular targeted agents as second-line treatment for hepatocellular carcinoma: a meta-analysis and review. Oncotarget. 8(60):102321-102327, 2017(SCI) 13. Kim JH, Kim HS, Kim BJ, Lee J, Jang HJ. Prognostic value of c-Met overexpression in pancreatic adenocarcinoma: a meta-analysis. Oncotarget. 22;8(42):73098-73104, 2017(SCI) 14. Jang HJ, Hong EM, Kim M, Kim JH, Jang J, Park SW, Byun HW, Koh DH, Choi MH, Kae SH, Lee J, Simvastatin induces heme oxygenase-1 via NF-E2-related factor 2 (Nrf2) activation through ERK and PI3K/Akt pathway in colon cancer. ONCOTARGET Vol. 7(29), pp. 46219~46229, 2016 15. Jang HJ, Hong EM, Park SW, Byun HW, Koh DH, Cho, MH, Kae SH, Lee J, Statin induces apoptosis of human colon cancer cells and downregulation of insulin-like growth factor 1 receptor via proapoptotic ERK activation. ONCOLOGY LETTERS Vol. 12(1), pp. 250~256, 2016 16. Jang HJ, Hong EM, Jang J, Choi JE, Park SW, Byun HW, Koh DH, Choi MH, Kae SH, Lee J, Synergistic Effects of Simvastatin and Irinotecan against Colon Cancer Cells with or without Irinotecan Resistance. GASTROENT RES PRACT Vol. 2016(2016), pp. ~, 2016 17. Lee J, Hong EM, Jang JA, Park SW, Koh DH, Choi MH, Jang HJ, Kae SH, Simvastatin Induces Apoptosis and Suppresses Insulin-Like Growth Factor 1 Receptor in Bile Duct Cancer Cells. GUT LIVER Vol. 10(2), pp. 310~317, 2016 18. Byun HW, Hong EM, Park SH, Koh DH, Choi MH, Jang HJ, Kae SH, Lee J. Pravastatin activates the expression of farnesoid X receptor and liver X receptor alpha in Hep3B cells. Hepatobiliary Pancreat Dis Int. 2014;13:65-73. 19. Dong SH, Lee J, Koh DH, Choi MH, Jang HJ, Kae SH. Pravastatin activates PPARalpha/PPARgamma expression in the liver and gallbladder epithelium of hamsters. Hepatobiliary Pancreat Dis Int 2011;10:185-190. 20. Lee J, Hong EM, Koh DH, Choi MH, Jang HJ, Kae SH, Choi HS. HMG-CoA reductase inhibitors (statins) activate expression of PPARalpha/PPARgamma and ABCA1 in cultured gallbladder epithelial cells.Dig Dis Sci. 2010 Feb;55(2):292-9. 21. Lee J, Hong EM, Byun HW, Choi MH, Jang HJ, Eun CS, Kae SH, Choi HS. The effect of PPARalpha and PPARgamma ligands on inflammation and ABCA1 expression in cultured gallbladder epithelial cells. Dig Dis Sci. 2008 Jun;53(6):1707-15. 22.. Eun CS, Han DS, Lee SH, Paik CH, Chung YW, Lee J, Hahm JS. Attenuation of colonic inflammation by PPARgamma in intestinal epithelial cells: effect on Toll-like receptor pathway. Dig Dis Sci. 2006 Apr;51(4):693-7. 23. Ji Kon Ryu, Jun Kyu Lee, Yong-Tae Kim, Dong Ki Lee, Dong Wan Seo, Kyu Taek Lee, Ho Gak Kim, Hong Sik Lee, Tae Nyeun Kim, Myung Hwan Rho, jong Ho Moon, Jin Lee, Ho-Soon Choi, Woo jin Lee, Byung Moo Yoo, Yong Bum Yoon: Clinical featurs of chronic pancreatits in Korea: a multicenter nationwide study. Digestion 72: 207-211, 2005. 24. Hyun Joo Jang, Geun Sook Kim, Jin Lee: Development of primary biliary cirrhosis in a patient with Crohn’s disease. Dig Dis Sci 50(12):2335-2337, 2005 25. Jin Lee: Lipid study using cultured biliary cells. Korean J Pancreas Biliary Tract 9:132-142, 2004 26. Jin Lee, Aimee Tauscher, Dong Wan Seo, John F. Oram, Rahul Kuver: Cultured gallbladder epithelial cells synthesize apolipoproteins A-I and E. Am J Physiol Gastrointest Liver Physiol. 285(3):G630-41, 2003. 27. Jin Lee, Andrew shirk, John F. Oram, Sum P. Lee, Rahul Kuver: Polarized cholesterol and phospholipid efflux in cultured gall-bladder epithelial cells: evidence for an ABCA1-mediated pathway Biochemical Journal 364: 475-484, 2002. 저서, 저술 1. 급성 충수염 진단에서 비조영증강 자기공명영상의 유용성: 복부초음파검사와 비교연구 2. When and how to treat gallbladder stone 3. The pathogenesis of cholesterol gallstone 4. 담낭결석과 담도결석의 치료: 내시경 치료 vs. 외과적 치료담낭상피세포에서 콜레스테롤 대사에 관련된 transporter 및 nuclear hormone receptor 5. 담낭 기능 보존에 있어서 PPAR의 역할 6. Helicobacter pylori 감염 1차 치료를 위한 삼제요법과 사제요법의 제균 효과 7. 담낭상피세포에 있어서 역콜레스테롤 수송 8. 담도계 세포를 이용한 지질대사연구 9. 담낭상피세포에 있어서 극성화된 콜레스테롤 및 인지질 유출에 대한 연구 모델의 개발 10. 위암에서 Telomerase 활성화와 Helicobacter pylori 감염의 연관성 |